Nghiên cứu đặc điểm lâm sàng bệnh tâm thần phân liệt đáp ứng kém với thuốc an thần kinh cổ điển và kết quả điều trị bằng thuốc clozapine tt tiếng anh

1. Prof. PhD Cao Tien Duc
2. Associate. Prof. PhD Bui Quang Huy
1. Military Medical University library – Ministry of Defense
2. National library of Vietnam
I. The urgency of the project
1. Review clinical features of schizophrenia in patients who
2. Evaluate results of treatment by clozapine for schizophrenic
3. Comment on the relationship between plasma levels of
2.1. Subjects
2.1.3. Selection criteria
3.1. The general characteristic of the research subjects
3.3. The results of treatment of schizophrenia respond poorly to
134.23 ±5.68 87.21 ± 3.65 64.59 ± 2.88
13.20 ± 1.87 8.08 ± 0.94 7.26 ± 0.73
3.97±0.89 2.46±0.53 1.98±0.13
4.84±0.61 4.44±0.53 2.23±0.42
4.82±0.39 4.47±0.57 2.28±0.45
4.56±0.53 3.95±0.28 2.33±0.47
3.84±0.37 2.95±0.22 2.00±0.00
4.49±0.50 2.34±0.48 2.00±0.00
4.64±0.52 2.74±0.44 2.28±0.45 p<0.001
4.28±0.58 2.11±0.32 2.00±0.00 p<0.01
4.82±0.39 2.51±0.54 2.25±0.43 p<0.001
4.21±0.49 2.08±0.28 2.00±0.00 p<0.001 p<0.05
3.4. Relationship between dose and Clozapine plasma level under
87.37±2.87 64.47±2.93
3.77±2.03 8.33±0.96 7.43±0.77
3.73±1.28 6.67±0.99 5.87±0.35
3.90±0.80 2.43±0.50 2.00±0.00 p<0.001
4.80±0.41 4.40±0.72 2.00±0.00
4.73±0.52 4.43±0.57 2.20±0.41 p<0.01
4.80±0.41 4.33±0.61 2.27±0.45
4.20±0.48 3.60±0.56 2.00±0.00